Filagra Double Action is a product containing Sildenafil citrate as it API (Active Pharmaceutical Ingredient) which is prescribed to men who have erectile dysfunction and impotence. Its manufacturer is Fortune Healthcare. Filagra has the same generic as Viagra, i.e. Sildenafil citrate. There is a wide range of Sildenafil citrate tablets and oral jelly products available in the market. All those products are indicated for the treatment of erectile dysfunction. The amount and composition of Sildenafil citrate are different in all preparations and some contain other ingredients added to enhance the effects and treat additional issues related to erectile dysfunction such as premature ejaculation. Filagra double action is a part of the huge range of products from Fortune Healthcare that includes Filagra 25 mg, Filagra 50 mg, Filagra 100 mg, Filagra DXT, Filagra FXT, among others.
Filagra double action, as claimed by it manufacturer, is a very powerful drug that would make the patient’s erections stronger and help improve their quality of life. Sildenafil citrate is given in varying doses and usual dose is 25 milligrams, 50 milligrams or 100 milligrams of Sildenafil citrate. The dose offered in this product i.e. the double action is 200 milligrams, which is the double of the regular dose and also the maximum dose that can be taken in a day.
Safety Information of Filagra Double Action
The dose of Filagra double action is quite high, though it is not included in overdose or misuse. This dosage is permissible but it should also be remembered that this is the highest dose allowed, above which, there are chances of the symptom of overdose and toxicities. These tablets are easy to identify and are available as black colored tablets that are triangular in shape, coming in a pack size of 10 pills. Some reviews say that it is more economical to buy the strength of 200 mg as compared to other dosages because there is a practice of taking the tablet in broken form.
Breaking the tablet is not very safe because the tablet is coated and the coating should not be disturbed. Broken fragments of the tablets can irritate the lining of the esophagus if any piece sticks to the inner wall of the esophagus. There are also high chances of improper dose distribution in the tablets and therapeutic failures can be experienced.
This product can be taken once a day at maximum and mostly taken as needed. The doses of Sildenafil citrate depend on the patient’s ability to tolerate the drug and also on the impact on different patients. Dosing is started at 25 mg and is increased to 50 mg; after the effects are assessed, the dose can be reduced if the patient gets the clinical benefit with an even low dose of 25 mg while there is also a chance of increasing the dose to 100 mg Sildenafil citrate if expected benefits are not obtained. Jumping to a high dose or double dose at once is very unsafe and can result in dangerous side effects. Only those patients who have taken 100 mg Sildenafil citrate and did not get appropriate results would be eligible for taking this product. Before starting the therapy, it must be made sure that the patient is not allergic to any excipient or formulation ingredients.
The usual dose of Sildenafil starts with 25 mg and 50 mg but with Filagra double action, one tablet containing 200 mg will be taken. This is the highest possible dose of this drug and should be taken 1 hour before sexual activity. There is not much information available on the dose dependent effects on the duration of action but according to the manufacturer, this product gives a longer duration of action due to its double dose. This medication can be taken with food, without food, and with plain water, as the patient wants. The medication must be taken as told by the doctor and the doctor would take complete medication and dietary history prior to prescribing any dose to the patient.
Effects and Adverse Events of Filagra Double Action
Sildenafil is a type 5 inhibitor of Phosphodiesterase enzyme. The process of erection is dependent upon the endothelial nitrate and cyclic Guanosine Monophosphate. The degradation of cyclic Guanosine Monophosphate is stopped by Sildenafil citrate and its levels increase in the body. The relaxation of the muscles and tissues of corpus cavernosum takes place during sexual stimulation and finally, there is an increase in the blood supply to the penis resulting in an erection that is stronger and is also quick to restore after an intercourse. According to the label claim, this drug is intended for use in patients who despite taking erectile dysfunction medications, experience weak erections and their difficulty to maintain erections persists.
The side effects of Sildenafil that are among the most commonly reported adverse events for this drug are visual disturbances, flushing, headache, and dyspepsia. Some other side effects such as insomnia, runny nose or nasal congestion, and epistaxis (nosebleeds) have also been reported. According to some reports, prolonged erections of more than four hours were caused by Sildenafil use. This effect can result in long-term damage to the tissues of the penis and damage the penis permanently.
Filagra double action affects human systems and organs, and this is the reason why its concomitant use with other drugs is mostly not recommended. The cardiovascular system, musculoskeletal system, ocular and nervous system are those mostly associated with adverse events of Sildenafil citrate. In case of hepatic impairment or renal damage, there is a need for dose adjustment or the doctor might decide not to make the patient start Sildenafil if risks to kidneys or liver are suspected.
Clinically significant interactions exist between Sildenafil citrate and some drugs for example nitrates, macrolides, some antifungal agents, antiviral agents, and other antibiotics. Many disease conditions are also affected by this agent such as heart diseases, hepatic failure, epilepsy and seizures, kidney diseases, lung diseases and ocular issues. Food usually does not affect the levels of Sildenafil citrate in the plasma but consuming alcohol with Sildenafil can result in hypotension and dizziness. There are high chances of losing balance and tripping over because of postural hypotension induced by alcohol. Another interaction that comes under alcohol and food interaction is Sildenafil’s interaction with grapefruit and grapefruit juice. It was revealed in some studies that grapefruit or its juice, when used in excessive or abnormal amounts, can raise the plasma drug concentrations of Sildenafil citrate which can be very dangerous especially in this case because the patient would already be receiving double strength of the usual dose. Cardiac risks are higher in patients with a past history of cardiac issues and the use of Sildenafil is not advisable in such patients. Clearance of Sildenafil depends majorly on the hepatic route and some proportion is cleared through renal route. Diseases affecting any of these organs can increase the plasma concentration of Sildenafil and might result in toxic levels of this drug in the body. Ocular damages can worsen if Sildenafil treatment is started without an eye examination of the patient.
There is no indication for the use of this drug in women. This drug is indicated for adult men and should be used when needed. The pregnancy category of this drug is B. It is not recommended for use in women with childbearing potential. Evidence of toxicity to the unborn child, teratogenicity, fetotoxicity and embryotoxicity were not found when animal trials were conducted on rats and rabbits. The risk still remains and there can be unwanted and unexpected outcomes if this product is ingested by a woman. There are some references that this drug is excreted into the breast milk.
For the patients, there are certain points to remember and to be careful about. This drug will be prescribed to a patient by his medical practitioner on the basis of risk-benefit ratio, which means that the doctor found it suitable for the patient and the potential risks were outweighed by the expected benefits of the drug. It is the patient’s responsibility to take care of his health and inform the doctor if any recent developments occur. In case the patient needs to start another medication while he is still using Filagra double action, he should consult a doctor and take his medications as told by the doctor. Erectile dysfunction is not just a disorder that affects the person’s physical processes, but it has many psychological impacts too. The person suffering from impotence or erectile dysfunction can develop some kind of anxiety, depression and inferiority complexes. Since the patient’s quality of life is affected by this problem, just prescribing a medication is not enough; the patient needs counseling and reassurance that this condition is curable and there is nothing to be worried about. Both the partners should be well aware of certain medical emergencies that might occur with the use of Sildenafil, though such emergencies are rare.