Filagra 100 Review: Affordable Sildenafil Treatment Reported Effective by Patients

Filagra 100 Pack

Filagra 100 is another generic remedy for erectile dysfunction (ED) which is from Fortune Healthcare from India. The “Filagra” product line is the term used by the manufacturer to denote its Sildenafil-containing products made for patients with erectile dysfunction. Some vendors call the product “generic Viagra” or “generic Revatio” [1]. The product, Filagra 100 contains 100 mg of Sildenafil Citrate (SC) in every pill, which is considered the maximum recommended dose for any Sildenafil-containing ED medication, according to the research “Clinical safety of oral sildenafil citrate (ViagraTM) in the treatment of erectile dysfunction” by Morales et.al. [2]. The usual minimum recommended dose for Sildenafil treatment is only 25-50 mg [2]. Filagra comes in 50 mg and 25 mg formulations too, though [1].

Sildenafil is the first discovered Phosphodiesterase type-5 inhibitor (PDE5i) for the treatment of erectile dysfunction in the male population. It was just discovered by accident [3], as Sildenafil was initially indicated for angina, although it was not as potent as it was expected to be. Later on, it was developed into the main drug for erectile dysfunction as it was complained by patients to cause an erectile effect.

Filagra products are Fortune Healthcare’s flagship sildenafil products and it comes in various forms aside from Filagra 100, the standard pill. There are oral jellies and soft tabs/sublingual available for users too.

Fortune Healthcare India in Perspective

As for Fortune Healthcare India, the manufacturer of the Fildena line of Sildenafil-containing products. It is a young company, as it is established just in the year 2004. The Fildena products like this Fildena 100 pills are common in the online pharmacy market, as these Fildena (generic) products are an affordable substitute for the brand-name erectile dysfunction products.

Fortune Healthcare India on a Map
Fortune Healthcare India on a Map

The company spoke of being conscious of its products’ quality, its product formulation, or its product content [4]. Although the company has yet to obtain its certification from the US Food and Drug Administration, it is already accredited by the World Health Organization (WHO) as it was found compliant to its Good Manufacturing Practice (GMP) [4]. Fortune Healthcare India specializes in men’s health medication, as it aims to “eradicate all men’s problems” [4] by providing the population cheaper access to quality and affordable medication.

Clinical Studies on Sildenafil Citrate

Although erectile dysfunction in the population is prevalent, ED in several patient populations with other medical conditions are not aware that they have erectile dysfunction coexisting with their present illnesses such as cardiovascular disease (CVD), lower urinary tract symptoms (LUTS), and diabetes. The study, “A multicenter, double-blind, placebo-controlled trial to assess the efficacy of sildenafil citrate in men with unrecognized erectile dysfunction” by Shabsigh et. al. intended to determine if Sildenafil treatment would be effective to the patient population who were unsure if they have ED or not [5]. The participants with ED-associated co-morbidities (CVD, diabetes, LUTS) but answered that they do not have ED or were unsure if they have ED were asked to participate in the study [5]. Not only was the erectile function assessed, but the emotional and psychosocial benefits brought about by Sildenafil were assessed as well [5]. The study concluded that these participants with ED-related co-morbidities (who were unaware they have ED) also had their erectile function improved by the drug [5]. The authors recommended that since ED is not only a physiological disease, men with risks of ED should be assessed for them to be treated accordingly and help them improve their quality of life, as ED also affects patients psychosocially [5].

Since cases of ED were also coinciding with LUTS, Eryildirim et.al. also studied whether Sildenafil Citrate has an effect on lower urinary system symptoms (LUTS) in the study “The effectiveness of sildenafil citrate in patients with erectile dysfunction and lower urinary system symptoms and the significance of asymptomatic inflammatory prostatitis” [6]. Sildenafil was proven effective in treating ED symptoms and managing LUTS in participants without asymptomatic inflammatory prostatitis. But, it was found out that in patients with the condition, Sildenafil is only able to treat the ED symptoms and not the LUTS [6].

Not all of Sildenafil-treated patients were responsive to treatment. There are patients, like those who were with type 2 diabetes mellitus with moderate to severe ED who were unresponsive to sildenafil treatment. The study conducted by Sun et.al., “Combined sildenafil with vacuum erection device therapy in the management of diabetic men with erectile dysfunction after the failure of first-line sildenafil monotherapy”, studied whether an adjunct treatment would aid the effectiveness of sildenafil to the patients unresponsive to treatment [7]. The researchers evaluated if the use of vacuum erection device therapy is effective in treating ED alone, but later on discovered that the device was not sufficient to treat the patients either. But, it was found out that when Sildenafil and the device were used together, erectile function and response were enhanced, and were well-tolerated by the patients than either of the two treatments alone [7].

Pharmacological Action of Sildenafil

Sildenafil functions as an oral agent which enhances the natural erectile function of patients who have lost their natural sexual response due to erectile dysfunction (ED) [2]. Sildenafil citrate enhances the effect of nitric oxide (NO) in relaxing the muscles of the penile corpus cavernosum. NO is the activator of guanylate cyclase, which results in increased synthesis of cGMP (cyclic guanosine monophosphate) [2]. cGMP results to smooth muscle relaxation of corpus cavernosum. Since Sildenafil specifically inhibits the action of PDE5 (phosphodiesterase type 5), which is responsible for the degradation of cGMP, the concentration of cGMP continues to rise, therefore maintaining the erectile response for long [2]. But for Sildenafil to work, sexual stimulation is still needed as Sildenafil may not cause erections on its own [2].

Sildenafil Effects

It is expected of Sildenafil to improve the sexual response of the patient taking it unless the patient has other comorbid medical conditions present. But almost all of the time, Sildenafil is expected to restore the lost erectile response of patients suffering from ED.

Filagra 100 contains Sildenafil citrate and in the highest recommended dose (100 mg), so patients can expect improved erectile function while on the drug. Patients can’t expect the drug to cause spontaneous erections, though, as Filagra or any SC-containing medication works only in the presence of sexual stimuli.

Recommended Doses and Duration of Therapy

Most patients are recommended only an initial dose of 50 mg and are advised to take the medication at least an hour before any sexual activity, but, it may be taken anywhere between 30 minutes to 4 hours prior to sexual activity, as the drug works well within the mentioned time frame [2]. Depending on the patient’s response to treatment, he may be prescribed a higher dose (100 mg) or a lower dose (25 mg) [2]. But no matter the dose, patients are strictly prohibited to take more than a dose of any Sildenafil drug in a day [2]. Since the drug is not a cure or a maintenance medication, there is no prescribed treatment length for taking Sildenafil drugs. Patients are only advised to take the medication as needed.

Side effects and Warnings

Like any other drug, Sildenafil is also known to have mild to moderate side effects. According to the study by Moreira et.al. (“Side-effect profile of sildenafil citrate (Viagra) in clinical practice”), frequently reported side effects of sildenafil-containing drugs include flushing (accounts for 30.8% of the incidences), headache (25.4%), nasal congestion (18.7%), and heartburn (10.5%) [8]. These side effects, however, were just transient and were quickly managed. None was reported to have discontinued SC treatment for ED due to the side effects, although 31% of the patient population experienced one or more side effects from the drug [8]. It was noted, however, that the side effects were associated with the higher dosing of the drug in patients [8].

Drug Interactions

There are a number of drug interactions known for Sildenafil products. Nitrates like nitroglycerin or those with isosorbide dinitrate for cardiovascular diseases are generally contraindicated for Sildenafil products, as the interaction may cause a rapid decrease in blood pressure [9]. Also, recreational drugs like “poppers” shouldn’t be taken with any Sildenafil product, as these have nitrates too [9].

Aside from nitrates, it is also prohibited to take in other ED medication along with Sildenafil, plus Cimetidine, Bosentan, Nefazodone, Antibiotics, St. John’s wort, Imatinib, Blood pressure/Heart meds, HIV meds, Antifungal meds, Seizure Meds, Hepa C meds, and Tuberculosis meds [9]. Grapefruit is also toxic when combined with Sildenafil as it prevents the drug’s breakdown, causing it to exist in the body in toxic levels [9].

Since these drugs are contraindicated for Sildenafil, Filagra 100 users should take caution regarding these drugs as Filagra has Sildenafil as its active pharmaceutical ingredient.

Customer Reviews

Filagra 100 Consumer Reports
Filagra 100 Consumer Reports

Users generally liked Filagra 100 as reflected by their reviews for the drug. One user from Fortunehealthcarestore.com rated Filagra 100 5/5 stars for being the “best” pill he ever tried. The buyer also mentioned that Filagra 100 is affordable.

Filagra 100 Reviews
Filagra 100 Reviews

A couple of reviewers more were spotted giving good reviews for Filagra 100 on Usrushed.com. The patients rated the site 4 and 5 out of 5 and it can be seen in their reviews that they were satisfied at how effective the drug was. Terry, one reviewer from the site, described that he was not the only one pleased, as his partner was also satisfied with the effect of Filagra 100.

Only good reviews were the ones available for Filagra 100, so it’s safe to say that the drug was generally well-liked by the buyers. It may be recommendable, as it was not only effective; according to one buyer, the product was affordable too.

Filagra 100 Price, Available Forms and Dosage

Filagra 100 Cost
Filagra 100 Cost

Fortunehealthcarestore.com sells Filagra 100 for a minimum of 10 pills, which costs $36, and is not a bad price for any type of ED medication, since the branded medications from well-known multi-national drug corporations are way more expensive than Filagra 100, even if they only have similar content.

Filagra 100 Price and Shipping
Filagra 100 Price and Shipping

As can be seen on the details of the image, some Internet pharmacies are able to sell Filagra for even lower as the quantity of the pills bought gets higher. In case with puretablets.com, users may purchase the product at a discounted rate when bought in greater quantities. As for the shipping fees charged, there is no standard fee charged across sites, and the vendors may charge as much as they please for the shipping. It is noticeable, though, that the shipping rate is similar for all countries, as the drugstores charge for the courier type and not really for the weight of the parcels.

Filagra 100 in Shipping Cart
Filagra 100 in Shipping Cart

Typical shipping rates to expect from the Internet drugstores range from at least $10 for the regular shipping. But some, like the Internet pharmacies mentioned above, charge at least $20. Some, charge for free, though. The Internet pharmacies are able to ship anywhere in the world—they can cater to clients from the USA, Canada, and Australia, plus a number of other countries more. And since the shipping rates are courier-dependent buyers can expect the same shipping rate per courier for all destinations anywhere in the world.

Conclusion and Rating

Sildenafil citrate’s effectiveness in treating erectile dysfunction of various causes with only little-known side effects makes it very popular among worldwide users. But since treatment costs have been too high, especially for international clients, pharmaceutical companies (upon the approval of the FDA), started manufacturing generic drugs with the same effective Sildenafil content. One such company is Fortune Healthcare in India, which is responsible for the Filagra product line, which is one of the popular SC products on the web.

Filagra 100 is only one of the several products made by Fortune Healthcare for the product line. Filagra 100 is 100 mg Sildenafil in hard pill form, but the company also has sublingual/soft tablets, oral jellies, and low strengths of Filagra regular tablets. The product is well-reviewed, and the users were very vocal about how they liked the product and how affordable the treatment was.

As for the rating, I think Filagra 100 deserves 4 out of 5, as it is both effective and affordable. Fortune Healthcare, though not yet approved by the US FDA, was already accredited by the WHO-GMP, which makes it reliable in terms of quality. It may be a good substitute for the expensive Sildenafil treatments but should be handled cautiously and taken only according to doctors’ recommendations.

Filagra 100 Wiki Facts

  • Brand: Filagra 100
  • Active Ingredient: Sildenafil Citrate
  • Treatment: Erectile Dysfunction
  • Manufacturer: Fortune Healthcare
  • Country of Manufacture: India
  • Availability: Netherlands, USA, UK, EU, India, Canada +

Reference List

  1. Generic Filagra. Available from: http://www.overthcounter.com/product/Filagra
  2. Morales A, Gingell C, Collins M, Wicker PA, Osterloh IH, Montorsi F, Wagner G. Clinical safety of oral sildenafil citrate (ViagraTM) in the treatment of erectile dysfunction. International journal of impotence research. 1998 Jun 1;10(2):69-74. Available from: https://www.researchgate.net/profile/Alvaro_Morales2/publication/13636709_Clinical_safety_of_oral_sildenafil_citrate_VIAGRA_TM_in_the_treatment_of_erectile_dysfunction/links/548eddbb0cf225bf66a7bd2d.pdf
  3. Jay E. Viagra and other drugs discovered by accident. BBC News. 2010.
  4. Fortune Healthcare India. About Us. Available from: http://fortunehealthcare.eworldtradefair.com/aboutus.html
  5. Shabsigh R, Kaufman J, Magee M, Creanga D, Russell D, Budhwani M. A multicenter, double-blind, placebo-controlled trial to assess the efficacy of sildenafil citrate in men with unrecognized erectile dysfunction. Urology. 2010 Aug 31;76(2):373-9. Available from: https://www.ncbi.nlm.nih.gov/pubmed/20579708
  6. Eryildirim B, Aktas A, Kuyumcuoglu U, Faydaci G, Tarhan F, Ozgül A. The effectiveness of sildenafil citrate in patients with erectile dysfunction and lower urinary system symptoms and the significance of asymptomatic inflammatory prostatitis. International journal of impotence research. 2010 Nov 1;22(6):349-54. Available from: https://www.ncbi.nlm.nih.gov/pubmed/20981108
  7. Sun L, Peng FL, Yu ZL, Liu CL, Chen J. Combined sildenafil with vacuum erection device therapy in the management of diabetic men with erectile dysfunction after failure of first‐line sildenafil monotherapy. International Journal of Urology. 2014 Dec 1;21(12):1263-7. Available from: https://www.ncbi.nlm.nih.gov/pubmed/25039272
  8. Moreira SG, Brannigan RE, Spitz A, Orejuela FJ, Lipshultz LI, Kim ED. Side-effect profile of sildenafil citrate (Viagra) in clinical practice. Urology. 2000 Sep 30;56(3):474-6. Available from: http://www.sciencedirect.com/science/article/pii/S009042950000649X
  9. What Is Viagra (Sildenafil)?. Available from: http://www.everydayhealth.com/drugs/viagra

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